Crass-like phage

Author: uugx

August undefined, 2024

WebOct 23, 2024 · Two of the 39 phage genomes — crAss-like phage and LoVEphage — showed remarkably high prevalence worldwide, at 20.6% and 14.4%, respectively. The researchers identified one as a crAss-like ... WebHere, using Cellulophaga baltica crAss-like phage phi14:2 as a model system, we show that this protein is a DNA-dependent RNAP that is translocated into the host cell along with the phage DNA and transcribes early phage genes. We determined the crystal structure of this 2,180-residue enzyme in a self-inhibited state, which probably occurs ...

GitHub - gbouras13/pharokka: fast phage annotation program

WebJan 16, 2024 · CrAss-like phage genomes assemble very easily out of metagenomic sequencing data, and the small genome size makes measuring strain diversity simple. While many methods have been developed to characterize strain diversity in bacteria, such as StrainPhlAn[12] PanPhlAn[13], our relatively simple read mapping approach worked … danny masterson trial nov 2021

Discovery, diversity, and functional associations of crAss-like …

WebAug 18, 2024 · CrAss-like phages are capable of long-term stable persistence in the mammalian gut and select for resistance in their bacterial host. We have previously … WebNov 14, 2024 · CrAssphages represent the most abundant virus in the human gut microbiota, but the lack of available genome sequences for comparison has kept them enigmatic. Recently, sequence-based classification of distantly related crAss-like phages from multiple environments was reported, leading to a proposed familial-level taxonomic … WebNov 29, 2024 · Some of the most striking phage counter-resistance mechanisms include alteration of phage DNA to evade host restriction modification mechanisms ( 63) and phage encoded CRISPR-Cas systems that target and disable a range of host defense systems ( 64 ). Ecological Relevance of Phage-Host Dynamics danny mathewson

Analysis of metagenome-assembled viral genomes from …

Acquisition, transmission and strain diversity of human gut …

WebApr 12, 2024 · By mapping metagenomic reads to the phage genomes (coverage ≥ 30%), we discovered that the prevalence of 2 GPIC phages (Parabacteroide phage PD491P1 29.5%, and Alistipes phage AS73P1 19.5%) was higher than that of the two isolated crAss-like phages (crAss001, 11.3% and crAss002, 14.5%) but lower than that of the prototype … WebApr 12, 2024 · By mapping metagenomic reads to the phage genomes (coverage ≥ 30%), we discovered that the prevalence of 2 GPIC phages (Parabacteroide phage PD491P1 … danny mathews dentist montgomeryWebAug 18, 2024 · The crAss-like phages are ubiquitous and highly abundant members of the human gut virome that infect commensal bacteria of the order Bacteroidales. Although incapable of lysogeny, these viruses demonstrate long-term persistence in the human gut microbiome, dominating the virome in some individuals. Results danny masterson who is he

"WebNov 14, 2024 · Here, we assembled the metagenomic sequencing reads from 702 human fecal virome/phageome samples and analyzed 99 complete circular crAss-like phage … " - Crass-like phage

Crass-like phage

Acquisition, transmission and strain diversity of human gut …

WebJun 1, 2024 · Assembly and identification of crAss-like phage genomes To identify crAss-like phage genomes in our gut metagenomic data, we assembled contigs for 2291 … WebFeb 26, 2024 · The crAss-like phages are therefore reminiscent of the concept of plasmid or phage plasmid (Lagos and Goldstein, 1987). Finally, coupling metaHiC with other approaches on larger human cohort will shed new lights and findings about the relationships between phages, plasmids, and bacteria.

Did you know?

WebFeb 28, 2024 · crAss-like phages possess unusual features of genome organization, for example, genes encoding giant proteins consisting of fused RNA polymerase subunits. The first crAss-like phage has been isolated and shown to infect Bacteroides intestinalis. Metagenomics is currently the primary means for identifying new viruses. The crAss-like phage bacteriophage family is considered highly diverse and consists of four subfamilies- alpha, beta, delta, and gamma- and ten genera within the subfamilies. The subfamilies are defined by crAss-like phage that share 20-40% of their protein-encoding genes while a genera is … See more CrAss-like phage are a bacteriophage (virus that infects bacteria) family that was discovered in 2014 by cross assembling reads in human fecal metagenomes. In silico comparative genomics and taxonomic analysis have … See more The crAss (cross-assembly) software used to discover the first crAss-like phage, p-crAssphage (prototypical-crAssphage), relies on cross assembling reads from multiple metagenomes obtained from the same environment. The goal of cross-assembly is that … See more CrAss-like phage have been identified as a highly abundant and near-universal member of the human gut microbiome. CrAss-like phage … See more • Newly-found gut virus 'abundant in humans' - BBC News • Why Has This Really Common Virus Only Just Been Discovered? - National Geographic See more The crAss-like phage have a podoviridae-like morphology with a tail structure similar to that of bacteriophage P22. Based on initial sequence-based studies of crAss-like phage, the bacteriophage family was predicted to consist of phage with a diversity of … See more Based on a sequence similarity screen of p-crAssphage protein sequences to protein sequences in public sequence databases and … See more

WebSep 29, 2024 · The adult sample contained a 191 kilobase crAss-like phage genome with the potential to circularize, and the infant sample had a 94 kilobase crAss-like phage genome, which was curated to ... WebJan 11, 2024 · The crAss-like phage taxonomic clusters involved in these associations included the entire crAss-like phage assemblage, groups beta and delta, and genus-level clusters alpha15, gamma1, gamma4, delta27, and epsilon1. All the bacteria involved in these associations belonged to the phyla Actinobacteria and Firmicutes.

WebJun 1, 2024 · Assembly and identification of crAss-like phage genomes To identify crAss-like phage genomes in our gut metagenomic data, we assembled contigs for 2291 metagenomic samples from four cohorts: 1135 LLD, 338 LLD follow-up, 298 300OB and 520 IBD samples. Contigs of 10 kilobases (kb) or longer were retained for further analysis. WebFast Phage Annotation Tool pharokka is a rapid standardised annotation tool for bacteriophage genomes and metagenomes. If you are looking for rapid standardised annotation of bacterial genomes, please use prokka, which inspired the creation of pharokka, or bakta. Documentation Check out the full documentation at …

WebApr 12, 2024 · The first crAss-like phage isolated, ΦcrAss001, infects B. intestinalis and is a member of the more heterogenous candidate genus VI of the sub-family …

WebApr 12, 2024 · The gut phageome comprises a complex phage community of thousands of individual strains, with a few highly abundant bacteriophages. CrAss-like phages, which … danny maude chipping golfWebFeb 26, 2024 · The crAss-like phages are therefore reminiscent of the concept of plasmid or phage plasmid (Lagos and Goldstein, 1987). Finally, coupling metaHiC with other … danny maude basic golf swingWebFeb 1, 2024 · Their genome sizes (Phage TG-crAlp-04 -100,626 bp, Phage TG-crAlp-06 -98,173 bp) fell in the general size range of crAss-like phages which are typically around 100 kb in size (Guerin et al., 2024). birthday invitations to printWebFeb 16, 2024 · Some of the crAss-like phage genomes (for example, Eld241-t0_s_1 of the delta group; Supplementary Fig. 7) contain almost no long ORFs when translated under … birthday invitations templates free onlineWebNov 13, 2024 · Some crAss-like phages encode additional, auxiliary proteins in the tail module, for example, an IAS protein homologous to the tail-associated lysozyme gp13 of … danny maude chipping golf videosWebMay 22, 2024 · A new crAss-like genome encoding diversity-generating retroelement (DGR) was found in the fecal virome of a healthy volunteer. The genome of the phage referred to as the crAssphage LMMB, belonged to the candidate genus I of the AlphacrAssvirinae subfamily. The DGR-cassette of the crAssphage LMMB contained all … birthday invitations with photoWebHowever, crAss-like phages, in this population, are dominated by the genera VI, VII and VIII. Interestingly, it also reveals the presence of a virus family, Sphaerolipoviridae, which has not been ... birthday invitations that don\u0027t ask for gifts